Bone marrow mesenchymal stem cell-derived exosomes attenuate cerebral ischemia-reperfusion injury-induced neuroinflammation and pyroptosis by modulating microglia M1/M2 phenotypes

Author:

Liu Xiaoli,Zhang Meimei,Liu Haining,Zhu Rui,He He,Zhou Yuqing,Zhang Yilei,Li Chen,Liang Donghui,Zeng Qing,Huang Guozhi

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Developmental Neuroscience,Neurology

Reference50 articles.

1. Interferon-gamma and interleukin-1Beta enhance the secretion of brain-derived Neurotrophic factor and promotes the survival of cortical neurons in brain injury;Abd-El-Basset;Neurosci Insig.,2020

2. GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes;Aglietti;Proc. Natl. Acad. Sci. U. S. A.,2016

3. Hispidulin exhibits neuroprotective activities against cerebral ischemia reperfusion injury through suppressing NLRP3-mediated pyroptosis;An;Life Sci.,2019

4. Comprehensive proteomic analysis of Mesenchymal stem cell Exosomes reveals modulation of angiogenesis via nuclear factor-KappaB signaling;Anderson;Stem Cells,2016

5. Validity and reliability of neurological scores in mice exposed to middle cerebral artery occlusion;Bieber;Stroke,2019

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