The alpha-synuclein mutation E46K promotes aggregation in cultured cells

Author:

Pandey Neeraj,Schmidt Robert E.,Galvin James E.

Publisher

Elsevier BV

Subject

Developmental Neuroscience,Neurology

Reference33 articles.

1. Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson’s disease and dementia with Lewy bodies;Baba;Am. J. Pathol.,1998

2. Alternating metabolic pathways in NGF-deprived sympathetic neurons affect caspase-independent death;Chang;J. Cell Biol.,2003

3. Huntington’s disease age-of-onset linked to polyglutamine aggregation nucleation;Chen;Proc. Natl. Acad. Sci. U. S. A.,2002

4. Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein;Choi;FEBS Lett.,2004

5. Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease;Conway;Nat. Med.,1998

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