The second generation mixed lineage kinase-3 (MLK3) inhibitor CLFB-1134 protects against neurotoxin-induced nigral dopaminergic neuron loss
Author:
Funder
Michael J. Fox Foundation for Parkinson's Research
Publisher
Elsevier BV
Subject
Developmental Neuroscience,Neurology
Reference44 articles.
1. Does neuronal loss in Parkinson's disease involve programmed cell death?;Andersen;Bioessays,2001
2. The mixed-lineage kinase inhibitor URMC-099 protects hippocampal synapses in experimental autoimmune encephalomyelitis;Bellizzi;Eneuro,2018
3. Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: Two approaches with therapeutic potential in the treatment of neurodegenerative disease;Burke;Pharmacology & therapeutics,2007
4. Polychlorinated biphenyl-induced reduction of dopamine transporter expression as a precursor to Parkinson's disease-associated dopamine toxicity;Caudle;Toxicological sciences: an official journal of the Society of Toxicology,2006
5. Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration;Caudle;J. Neurosci.,2007
Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Selective Degradation of MLK3 by a Novel CEP1347-VHL-02 PROTAC Compound Limits the Oncogenic Potential of TNBC;Journal of Medicinal Chemistry;2024-08-29
2. Design, synthesis of new 3H-imidazo[4,5-b]pyridine derivatives and evaluation of their inhibitory properties as mixed lineage kinase 3 inhibitors;Bioorganic & Medicinal Chemistry Letters;2024-03
3. Infectious Diseases;Advances in Neurobiology;2024
4. The emerging role of mixed lineage kinase 3 (MLK3) and its potential as a target for neurodegenerative diseases therapies;European Journal of Medicinal Chemistry;2023-09
5. Kinases control of regulated cell death revealing druggable targets for Parkinson’s disease;Ageing Research Reviews;2023-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3