LRRK2, a puzzling protein: Insights into Parkinson's disease pathogenesis-Reference-Cited by-同舟云学术

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LRRK2, a puzzling protein: Insights into Parkinson's disease pathogenesis

Published:2014-11 Issue: Volume:261 Page:206-216
ISSN:0014-4886
Container-title:Experimental Neurology
language:en
Short-container-title:Experimental Neurology

Author:

Esteves A. Raquel,Swerdlow Russell H.,Cardoso Sandra M.

Funder

Portuguese Foundation for Science and Technology

University of Kansas Alzheimer's Center

NIH

Publisher

Elsevier BV

Subject

Developmental Neuroscience,Neurology

Reference168 articles.

1. LRRK2 is a component of granular alpha-synuclein pathology in the brainstem of Parkinson's disease;Alegre-Abarrategui;Neuropathol. Appl. Neurobiol.,2008

2. LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model;Alegre-Abarrategui;Hum. Mol. Genet.,2009

3. Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine);Andres-Mateos;J. Neurosci.,2009

4. Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death;Angeles;Hum. Mutat.,2011

5. LRRK2 phosphorylates novel tau epitopes and promotes tauopathy;Bailey;Acta Neuropathol.,2013

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1. Transcriptomics and weighted protein network analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson’s Disease;npj Parkinson's Disease;2024-08-03

2. Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors;Hepatology;2024-07-02

3. Biphenotypic Cells and α-Synuclein Accumulation in Enteric Neurons of Leucine-Rich Repeat Kinase 2 Knockout Mice;Digestive Diseases and Sciences;2024-06-07

4. LRRK2 kinase inhibition protects against Parkinson's disease-associated environmental toxicants;Neurobiology of Disease;2024-06

5. Decoding Inhibitor Egression from Wild-Type and G2019S Mutant LRRK2 Kinase: Insights into Unbinding Mechanisms for Precision Drug Design in Parkinson’s Disease;The Journal of Physical Chemistry B;2024-06-01

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