Serum Leptin Levels in Patients with Allergic Rhinitis-Reference-Cited by-同舟云学术

Serum Leptin Levels in Patients with Allergic Rhinitis

Published:2006-02 Issue:2 Volume:134 Page:331-333
ISSN:0194-5998
Container-title:Otolaryngology–Head and Neck Surgery
language:en
Short-container-title:Otolaryngol Head Neck Surg

Author:

Ünal Murat¹²,Eskandari Gülçin¹³,Muşlu Necati¹³,Pata Yavuz Selim¹²,Akbaş Yücel¹²

Affiliation:

1. Mersin, Turkey

2. Departments of Otorhinolaryngology, Mersin University, School of Medicine

3. Biochemistry, Mersin University, School of Medicine

Abstract

OBJECTIVE: To investigate the serum leptin levels in patients with allergic rhinitis during the symptomatic period. STUDY DESIGN AND SETTING: A randomized, prospective study was performed on 26 adult patients with allergic rhinitis and 20 control subjects with similar age, sex and body mass index in a tertiary otolaryngology center. RESULTS: Leptin levels were 28.8 ± 14.1 ng/mL in the patients with allergic rhinitis, and 20.8 ± 13.5 ng/mL in the control group respectively. The difference between the groups was statistically significant (p = 0.04). CONCLUSION: Serum leptin levels were found to be significantly higher in patients with allergic rhinitis in symptomatic period. SIGNIFICANCE: Apart from its primary role in the regulation of body weight and energy expenditure, leptin may have a role in the inflammatory process of the allergic rhinitis.

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Surgery

Link

http://journals.sagepub.com/doi/pdf/10.1016/j.otohns.2005.11.021

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