Evaluation of tumor oxygenation by color duplex sonography: A new approach-Reference-Cited by-同舟云学术

Evaluation of tumor oxygenation by color duplex sonography: A new approach

Published:2005-05 Issue:5 Volume:132 Page:765-769
ISSN:0194-5998
Container-title:Otolaryngology–Head and Neck Surgery
language:en
Short-container-title:Otolaryngol Head Neck Surg

Author:

Martino Ercole F.N. Di¹²³,Gagel Bernd¹²³,Schramm Oliver¹²³,Maneschi Payam¹²³,Westhofen Martin¹²³

Affiliation:

1. From the Departments of Oto-Rhino-Laryngology and Plastic Head and Neck Surgery (Drs Di Martino, Maneschi, and Westhofen)

2. Radiotherapy (Dr Gagel) Aachen University

3. The Department of Radiology (Dr Schramm), University of Heidelberg.

Abstract

OBJECTIVE: Description of a new noninvasive method for the evaluation of tissue oxygenation in head and neck cancer. STUDY DESIGN AND SETTING: Prospective nonrandomized controlled study in an academic medical center on 20 patients with neck metastases of head and neck cancer. Metastases were investigated using color duplex sonography and pO2 histography. The vascularization in sonography was quantitatively evaluated by color pixel density and compared to the pO2 values of the same nodes. RESULTS: The correlation between vascularization and flow velocity was 0.71. For the mean/median pO2-values and for the pO2 readings < 10.0 mmHg correlations were r = 0.65/0.76 and 0.71. CONCLUSION: This sonographic method allows a safe and reliable evaluation of oxygenation in metastases of head and neck cancer. SIGNIFICANCE: The new approach is an alternative to pO2 histography and may play a future role in the planning of radiotherapy in the neck. (Otolaryngol Head Neck Surg 2005;132:765-9.)

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Surgery

Link

http://journals.sagepub.com/doi/pdf/10.1016/j.otohns.2005.01.033

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