Hearing Loss with Semicircular Canal Transection and Pseudomonas Aeruginosa Otitis Media-Reference-Cited by-同舟云学术

Hearing Loss with Semicircular Canal Transection and Pseudomonas Aeruginosa Otitis Media

Published:2004-09 Issue:3 Volume:131 Page:248-252
ISSN:0194-5998
Container-title:Otolaryngology–Head and Neck Surgery
language:en
Short-container-title:Otolaryngol Head Neck Surg

Author:

Prevatt Angela R.¹²,Sedwick Jack D.¹²,Gajewski Byron J.¹²,Antonelli Patrick J.¹²

Affiliation:

1. Gainesville, Florida, and Kansas City, Kansas

2. Department of Otolaryngology, University of Florida and the University of Kansas Medical Center School of Nursing

Abstract

OBJECTIVE: To determine if Pseudomonas aeruginosa (PA) otitis media (OM) increases the risk of sensorineural hearing loss (SNHL) with semicircular canal transection in the guinea pig model. METHODS: PA was injected transtympanically into both middle ears of pigmented guinea pigs. Saline-injected animals served as controls. Two to 4 days after injection, one horizontal semicircular canal was transected and sealed. Hearing was tested using electrocochleography before and after transection. RESULTS: PA-OM was induced in all PA-injected ears. Five days after semicircular canal transection, click-evoked thresholds were significantly elevated in ears with PA-OM ( P = 0.00009) but not in saline-injected ears ( P = 0.398). CONCLUSION: Violation of the inner ear in the presence of PA-OM is associated with increased risk of SNHL in the guinea pig. SIGNIFICANCE: Factors unique to PA infection may be responsible for SNHL with labyrinthine injury in humans with chronic otitis media.

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Surgery

Link

http://journals.sagepub.com/doi/pdf/10.1016/j.otohns.2004.01.017

Reference22 articles.

1. Immediate and Short-Term Complications of Chronic Ear Surgery

2. CHOLESTEATOMA SURGERY

3. Opening of the Labyrinth During Chronic Ear Surgery

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