Laryngeal Inflammation Assessed using the Reflux Finding Score in Obstructive Sleep Apnea-Reference-Cited by-同舟云学术

Laryngeal Inflammation Assessed using the Reflux Finding Score in Obstructive Sleep Apnea

Published:2006-05 Issue:5 Volume:134 Page:836-842
ISSN:0194-5998
Container-title:Otolaryngology–Head and Neck Surgery
language:en
Short-container-title:Otolaryngol Head Neck Surg

Author:

Payne Richard J.¹²,Kost Karen M.¹³,Frenkiel Saul¹²,Zeitouni Anthony G.¹³,Sejean George¹⁴,Sweet Robert C.¹,Naor Naftaly¹,Hernandez Lourdes¹,Kimoff R. John¹

Affiliation:

1. Montreal, Canada

2. Department of Otolaryngology-Head and Neck Surgery, Jewish General Hospital, McGill University

3. Department of Otolaryngology-Head and Neck Surgery, Royal Victoria Hospital, McGill University

4. Division of Otolaryngology-Head and Neck Surgery, St. Mary's Hospital; Department of Otolaryngology-Head and Neck Surgery, Montreal General

Abstract

OBJECTIVES: To evaluate the relationships between laryngeal inflammation assessed using the Reflux Finding Score (RFS), laryngeal sensory function, and apnea severity in patients with obstructive sleep apnea (OSA). METHODS: Endoscopic sensory testing (EST) was performed with subsequent blinded scoring from video of RFS. An RFS > 7 was indicative of increased inflammatory change. RESULTS: Of 34 patients evaluated, 29 had OSA (apneahypopnea index [AHI] ≥ 15 events/h) at polysomnography. Increased inflammation was present in 26/29 (90%), with changes suggestive of laryngopharyngeal reflux. There were significant correlations between: inflammation and OSA severity (eg, RFS vs AHI, r = 0.57, P < 0.001); inflammation and laryngeal sensory impairment (EST detection threshold and pressure required to elicit the laryngeal adductor reflex, LAR); and the degree of sensory impairment and OSA severity. CONCLUSIONS: Laryngeal inflammation is prevalent among OSA patients and correlates with laryngeal sensory dysfunction, attenuation of the LAR, and apnea severity. EBM rating: C-4

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Surgery

Link

http://journals.sagepub.com/doi/pdf/10.1016/j.otohns.2006.01.012

Reference27 articles.

1. The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults

2. Upper Airway Sensation in Snoring and Obstructive Sleep Apnea

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