Novel immunocompetent murine tumor models for the assessment of replication-competent oncolytic adenovirus efficacy

Author:

Halldén Gunnel,Hill Richard,Wang Yaohe,Anand Arthi,Liu Ta-Chiang,Lemoine Nick R,Francis Jennelle,Hawkins Lynda,Kirn David

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference52 articles.

1. Replication-selective micro-organisms;Kirn;J. Clin. Invest.,2000

2. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells;Bischoff;Science,1996

3. ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents;Heise;Nat. Med.,1997

4. Identification of the transcriptional regulatory sequences of human kallikrein 2 and their use in the construction of calydon virus 764, an attenuated replication competent adenovirus for prostate cancer therapy;Yu;Cancer Res.,1999

5. The addition of adenovirus region E3 enables calydon virus 787 to eliminate distant prostate tumor xenografts;Yu;Cancer Res.,1999

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