A thirteen-week oral toxicity study of annatto extract (norbixin), a natural food color extracted from the seed coat of annatto (Bixa orellana L.), in Sprague–Dawley rats

Author:

Hagiwara A,Imai N,Ichihara T,Sano M,Tamano S,Aoki H,Yasuhara K,Koda T,Nakamura M,Shirai T

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference17 articles.

1. The role of annatto in food colouring;Collins;Food Ingredients and Processing International February,1992

2. A multiple comparison procedure for comparing several treatments with a control;Dunnett;Journal American Statistical Association,1955

3. Annatto;Evans;Biologist (London),2000

4. Norbixin ingestion did not induce any detectable DNA breakage in liver and kidney but caused a considerable impairment in plasma glucose levels of rats and mice;Fernandes;The Journal of Nutritional Biochemistry,2002

5. Statistical methods and scientific induction;Fisher;Journal of the Royal Statistical Society, Series “B”,1955

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