Once daily dolutegravir (S/GSK1349572) in combination therapy in antiretroviral-naive adults with HIV: planned interim 48 week results from SPRING-1, a dose-ranging, randomised, phase 2b trial

Author:

van Lunzen Jan,Maggiolo Franco,Arribas José R,Rakhmanova Aza,Yeni Patrick,Young Benjamin,Rockstroh Jürgen K,Almond Steve,Song Ivy,Brothers Cindy,Min Sherene

Publisher

Elsevier BV

Subject

Infectious Diseases

Reference19 articles.

1. Integrase inhibitors to treat HIV/AIDS;Pommier;Nat Rev Drug Discov,2005

2. Raltegravir versus efavirenz regimens in treatment-naive HIV-1 infected patients: 96-week efficacy, durability, subgroup, safety, and metabolic analyses;Lennox;J Acquir Immune Defic Syndr,2010

3. Raltegravir with optimized background therapy for resistant HIV-1 infection;Steigbigel;N Engl J Med,2008

4. Eron J, Rockstroh J, Reynes J, et al. QDMRK, a phase III study of the safety and efficacy of once-daily vs twice daily RAL in combination therapy for treatment-naïve HIV-infected patients. 18th Conference on Retroviruses and Opportunistic Infections; Boston, MA, USA; February 27–March 2, 2011. Abstr 150LB.

5. Elvitegravir, an oral HIV integrase inhibitor, for the potential treatment of HIV infection;Klibanov;Curr Opin Investig Drugs,2009

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