Antiepileptic drug discovery: Does mechanism of action matter?
Author:
Publisher
Elsevier BV
Subject
Behavioral Neuroscience,Neurology (clinical),Neurology
Reference12 articles.
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3. The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate;Wuttke;Mol Pharmacol,2005
4. The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels;Errington;Mol Pharmacol,2008
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1. Single-Target Versus Multi-Target Drugs Versus Combinations of Drugs With Multiple Targets: Preclinical and Clinical Evidence for the Treatment or Prevention of Epilepsy;Frontiers in Pharmacology;2021-10-27
2. Antiepileptic Drugs in Clinical Development: Differentiate or Die?;Current Pharmaceutical Design;2018-02-09
3. Strengthening the Case for Epilepsy Drug Development: Bridging Experiences from the Alzheimer’s Disease Field—An Opinion;Neurochemical Research;2017-06-07
4. Potential role of selected antiepileptics used in neuropathic pain as human GABA transporter isoform 1 (GAT1) inhibitors—Molecular docking and pharmacodynamic studies;European Journal of Pharmaceutical Sciences;2017-01
5. Drug treatment strategies for epilepsy revisited: starting early or late? One drug or several drugs?;Epileptic Disorders;2016-12
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