Expression of ACE2, the SARS-CoV-2 Receptor, and TMPRSS2 in Prostate Epithelial Cells

Author:

Song HanbingORCID,Seddighzadeh Bobak,Cooperberg Matthew R.ORCID,Huang Franklin W.

Funder

National Cancer Institute

Prostate Cancer Foundation

U.S. Department of Defense

National Institutes of Health

Publisher

Elsevier BV

Subject

Urology

Reference6 articles.

1. World Health Organization. Coronavirus disease (COVID-19) pandemic. www.who.int/emergencies/diseases/novel-coronavirus-2019.

2. Purdie A, Hawkes S, Buse K, et al. Sex, gender and COVID-19: disaggregated data and health disparities. BMJ Global Health blog. https://blogs.bmj.com/bmjgh/2020/03/24/sex-gender-and-covid-19-disaggregated-data-and-health-disparities/.

3. Hoffmann M, Kleine-Weber H, Schroeder S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. In press. https://doi.org/10.1016/j.cell.2020.02.052.

4. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer;Tomlins;Science,2005

5. A cellular anatomy of the normal adult human prostate and prostatic urethra;Henry;Cell Reports,2018

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