Dystrophin-deficiency increases the susceptibility to doxorubicin-induced cardiotoxicity

Author:

Deng Shiwei1,Kulle Bettina2,Hosseini Mehdi3,Schlüter Gregor3,Hasenfuss Gerd4,Wojnowski Leszek1,Schmidt Albrecht4

Affiliation:

1. Department of Pharmacology; Johannes Gutenberg University; 55101 Mainz Germany

2. Department of Biostatistics and Department of Mathematics; University of Oslo; Norway

3. Department of Human Genetics; University of Göttingen; 37075 Göttingen Germany

4. Department of Cardiology and Pneumology; University of Göttingen; 37075 Gottingen Germany

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine

Reference36 articles.

1. Anthracycline-induced cardiotoxicity: clinical course, risk factors, pathogenesis, detection and prevention-review of the literature;Wojtacki;Med Sci Monit,2000

2. Anthracycline-induced cardiomyopathy;Keefe;Semin Oncol,2001

3. Cardiac toxicity 4 to 20 years after completing anthracycline therapy;Steinherz;JAMA,1991

4. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin;Gewirtz;Biochem Pharmacol,1999

5. Adriamycin-induced free radical formation in the perfused rat heart: implications for cardiotoxicity;Rajagopalan;Cancer Res,1988

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