Molecular cloning, expression and characterization of the first three genes in the mevalonate-independent isoprenoid pathway in Streptomyces coelicolor

Author:

Cane David E,Chow Cathy,Lillo Antonietta,Kang Ilgu

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference40 articles.

1. Tavormina, P. A.; Gibbs, M. H.; Huff, J. W. J. Am. Chem. Soc. 1956, 78, 4498. Spurgeon, S. L.; Porter, J. W. In Biosynthesis of Isoprenoid Compounds; Porter, J. W., Spurgeon, S. L., Eds.; Wiley: New York, 1981; pp 1–46.

2. Rohmer, M. In Comprehensive Natural Products Chemistry. Isoprenoids Including Carotenoids and Steroids; Cane, D. E., Vol. Ed.; Barton, D., Nakanishi, K., Meth-Cohn, O., Eds.; Elsevier: Oxford, 1999; Vol. 2, pp 45–67. Rohmer, M. Nat. Prod. Rep. 1999, 16, 565. Schwarz, M.; Arigoni, D. In Comprehensive Natural Products Chemistry. Isoprenoids Including Carotenoids and Steroids; Cane, D. E., Vol. Ed.; Barton, D., Nakanishi, K., Meth-Cohn, O., Eds.; Elsevier: Oxford, 1999; Vol. 2, pp 367–400.

3. A new metabolite from Streptomyces hygroscopicus. I. Fermentation and isolation.

4. Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol

5. Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis

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