Identification of novel mammalian squalene synthase inhibitors using a three-Dimensional pharmacophore-Reference-Cited by-同舟云学术

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Identification of novel mammalian squalene synthase inhibitors using a three-Dimensional pharmacophore

Published:2002-08 Issue:8 Volume:10 Page:2641-2656
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Fairlamb Ian J.S.,Dickinson Julia M.,O'Connor Rachael,Higson Seamus,Grieveson Lynsey,Marin Veronica

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference52 articles.

1. Chemistry and Biology of the Zaragozic Acids(Squalestatins)

2. Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins

3. Rational design of potent carboxylic acid based bisubstrate inhibitors of ras farnesyl protein transferase

4. PROTEIN ISOPRENYLATION AND METHYLATION AT CARBOXYL-TERMINAL CYSTEINE RESIDUES

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3. Discovery of Potential Inhibitors of Squalene Synthase from Traditional Chinese Medicine Based on Virtual Screening and In Vitro Evaluation of Lipid-Lowering Effect;Molecules;2018-04-28

4. SAR studies on hydropentalene derivatives—Important core units of biologically active tetramic acid macrolactams and ptychanolides;Bioorganic & Medicinal Chemistry;2014-07

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