Susceptibility differences in chemical carcinogenesis linearize the dose–response relationship: threshold doses can be defined only for individuals

Author:

Lutz Werner K.

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics,Molecular Biology

Reference18 articles.

1. C.C. Harris, Chemical and physical carcinogenesis: advances and perspectives for the 1990s, Cancer Res. (Suppl.) 51 (1991) 5023s–5044s.

2. Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis;Weinstein;Carcinogenesis,2000

3. Background DNA damage from endogenous and unavoidable exogenous carcinogens: a basis for spontaneous cancer incidence;Gupta;Mutat. Res.,1999

4. Time as a determinant of risk in cancer epidemiology: the role of multi-stage models;Day;Cancer Surv.,1983

5. Cancer risk and low-penetrance susceptibility genes in gene-environment interactions;Shields;J. Clin. Oncol.,2000

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