Challenge to the simple paradigm that `carcinogens' are `mutagens' and to the in vitro and in vivo assays used to test the paradigm-Reference-Cited by-同舟云学术

Challenge to the simple paradigm that `carcinogens' are `mutagens' and to the in vitro and in vivo assays used to test the paradigm

Published:1997-02 Issue:2 Volume:373 Page:245-249
ISSN:0027-5107
Container-title:Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
language:en
Short-container-title:Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Author:

Trosko James E

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics,Molecular Biology

Reference44 articles.

1. Burgstahler, A.W. (1966) Detroit Fluoride conference. Science, 154, 590; Weinberg, R.A. (1996) E2F and cell proliferation: A world turned upside down. Cell 85, 457–459.

2. Trosko, J.E. (1984) A new paradigm is needed in toxicology evaluation. Environ. Mutagen., 6, 767–769.

3. Trosko, J.E. (1988) A failed paradigm: Carcinogenesis is more than mutagenesis. Mutagenesis, 3, 363–364.

4. Trosko, J.E. (1995) Dose-response studies of genotoxic rodent carcinogens; Thresholds, hockey sticks, hormesis or straight lines: A Reply. Belle Newslett., 3, 10–14.

5. Trosko, J.E. and Chang, C.C. (1985) Implications for risk assessment of genotoxic mechanisms in carcinogenesis, in: V.B. Vouk, G.C. Butler, D.G. Hoel and D.B. Peakall (Eds.), Methods for Estimating Risk of Chemical Injury: Human and Non-Human Biota and Ecosystems. John Wiley & Sons: Chichester, England, pp. 181–200.

Cited by 43 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. From Radiation Genetics, Mutagenesis, Gap Junctions, Epigenetics, Stem Cells and an Integration of Radiation and Chemical Carcinogenesis;Radiation Research;2024-06-07

2. The Concept of “Cancer Stem Cells” in the Context of Classic Carcinogenesis Hypotheses and Experimental Findings;Life;2021-11-27

3. What Can Chemical Carcinogenesis Shed Light on the LNT Hypothesis in Radiation Carcinogenesis?;Dose-Response;2019-07-01

4. A Historical Perspective for the Development of Mechanistic-Based 3D Models of Toxicology Using Human Adult Stem Cells;Toxicological Sciences;2018-08-28

5. Reflections on the use of 10 IARC carcinogenic characteristics for an objective approach to identifying and organizing results from certain mechanistic studies;Toxicology Research and Application;2017-01-01