Conversion of the neurotoxic precursor 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine into its pyridinium metabolite by human platelet monoamine oxidase type B

Author:

Da Prada M.,Cesura A.M.,Kettler R.,Zürcher G.,Haefely W.E.

Publisher

Elsevier BV

Subject

General Neuroscience

Reference22 articles.

1. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine;Burns,1983

2. Potent and long-lasting potentiation of two 5-hydroxytryptophan-induced effects in mice by three selective 5-HT uptake inhibitors;Buus-Lassen;Europ. J. Pharmacol.,1978

3. Aetiology of Parkinson's disease;Calne;Lancet,1983

4. Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP);Castagnoli;Life Sci.,1985

5. Effect of monoamine liberators on the metabolism of 5-hydroxytryptamine in blood platelets;Da Prada;Biochem. Pharmacol.,1965

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