A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity-Reference-Cited by-同舟云学术

A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity

Published:2024-05 Issue:5 Volume:5 Page:101553
ISSN:2666-3791
Container-title:Cell Reports Medicine
language:en
Short-container-title:Cell Reports Medicine

Author:

Liu Chang,Zhou Daming,Dijokaite-Guraliuc Aiste,Supasa Piyada,Duyvesteyn Helen M.E.,Ginn Helen M.,Selvaraj Muneeswaran,Mentzer Alexander J.,Das Raksha,de Silva Thushan I.,Ritter Thomas G.,Plowright Megan,Newman Thomas A.H.,Stafford Lizzie,Kronsteiner Barbara,Temperton Nigel,Lui Yuan,Fellermeyer Martin,Goulder Philip,Klenerman Paul,Dunachie Susanna J.,Barton Michael I.,Kutuzov Mikhail A.,Dushek Omer,Fry Elizabeth E.,Mongkolsapaya Juthathip,Ren Jingshan,Stuart David I.^ORCID,Screaton Gavin R.

Publisher

Elsevier BV

Reference57 articles.

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4. Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody;Pinto;Nature,2020

5. Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike;Liu;Nature,2020

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1. AlphaFold2 Modeling and Molecular Dynamics Simulations of the Conformational Ensembles for the SARS-CoV-2 Spike Omicron JN.1, KP.2 and KP.3 Variants: Mutational Profiling of Binding Energetics Reveals Epistatic Drivers of the ACE2 Affinity and Escape Hotspots of Antibody Resistance;Viruses;2024-09-13

2. SARS-CoV-2 JN.1 variant evasion of IGHV3-53/3-66 B cell germlines;Science Immunology;2024-08-09

3. Deep mutational scanning of SARS-CoV-2 Omicron BA.2.86 and epistatic emergence of the KP.3 variant;2024-07-24

4. Atomistic Prediction of Structures, Conformational Ensembles and Binding Energetics for the SARS-CoV-2 Spike JN.1, KP.2 and KP.3 Variants Using AlphaFold2 and Molecular Dynamics Simulations: Mutational Profiling and Binding Free Energy Analysis Reveal Epistatic Hotspots of the ACE2 Affinity and Immune Escape;2024-07-10

5. Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1;2024-04-22