Systematic analysis of off-label and off-guideline cancer therapy usage in a real-world cohort of 165,912 US patients

Author:

Liu Ruishan,Wang Lisa,Rizzo Shemra,Garmhausen Marius Rene,Pal Navdeep,Waliany Sarah,McGough Sarah,Lin Yvonne G.,Huang Zhi,Neal Joel,Copping Ryan,Zou JamesORCID

Funder

Roche

Stanford University

Publisher

Elsevier BV

Reference47 articles.

1. Off-label drug use in oncology: a systematic review of literature;Saiyed;J. Clin. Pharm. Therapeut.,2017

2. Level of evidence used in recommendations by the National Comprehensive Cancer Network (NCCN) guidelines beyond Food and Drug Administration approvals;Kurzrock;Ann. Oncol.,2019

3. Off-Label Drug Use in Cancer Treatment, https://www.cancer.gov/about-cancer/treatment/drugs/off-label.

4. Guidance for Industry - IND Exemptions for Studies of Lawfully Marketed Drug or Biological Products for the Treatment of Cancer, https://www.fda.gov/files/drugs/published/IND-Exemptions-for-Studies-of-Lawfully-Marketed-Drug-or-Biological-Products-for-the-Treatment-of-Cancer.pdf.

5. Off-label use of anticancer drugs;Levêque;Lancet Oncol.,2008

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