Combined Point-of-Care Nucleic Acid and Antibody Testing for SARS-CoV-2 following Emergence of D614G Spike Variant

Author:

Mlcochova Petra,Collier Dami,Ritchie AllysonORCID,Assennato Sonny M.,Hosmillo Myra,Goel NehaORCID,Meng Bo,Chatterjee Krishna,Mendoza Vivien,Temperton Nigel,Kiss LeoORCID,James Leo C.,Ciazynska Katarzyna A.ORCID,Xiong XiaoliORCID,Briggs John A.G.,Nathan James A.ORCID,Mescia FedericaORCID,Bergamaschi Laura,Zhang Hongyi,Barmpounakis Petros,Demeris Nikos,Skells Richard,Lyons Paul A.ORCID,Bradley John,Baker Steven,Allain Jean Pierre,Smith Kenneth G.C.,Bousfield Rachel,Wilson MichaelORCID,Sparkes DominicORCID,Amoroso Glenn,Gkrania-Klotsas EffrosyniORCID,Hardwick SusieORCID,Boyle AdrianORCID,Goodfellow Ian,Gupta Ravindra K.ORCID,Baker Stephen,Bradley John,Dougan Gordon,Goodfellow Ian,Gupta Ravi,Lehner Paul J.,Lyons Paul,Matheson Nicholas J.,Smith Kenneth G.C.,Toshner Mark,Weekes Michael P.,Brown Nick,Curran Martin,Palmar Surendra,Zhang Hongyi,Enoch David,Chapman Daniel,Shaw Ashley,Jose Sherly,Bermperi Areti,Zerrudo Julie Ann,Kourampa Evgenia,Watson Laura,Worsley Jieniean,Saunders Caroline,de Jesus Ranalie,Domingo Jason,Pasquale Ciro,Vergese Bensi,Vargas Phoebe,Fabiculana Marivic,Perales Marlyn,Mynott Lee,Blake Elizabeth,Bates Amy,Vallier Anne-Laure,Williams Alexandra,Phillips David,Chiu Edmund,Overhill Alex,Ramenatte Nicola,Sipple Jamal,Frost Steven,Knock Helena,Hardy Richard,Foster Emily,Davidson Fiona,Rundell Viona,Bundi Purity,Abeseabe Richmond,Clark Sarah,Vicente Isabel,Watson Laura,Worsley Jieniean,Elmer Anne,Ribeiro Carla,Kourampa Jenny,Jose Sherly,Kennet Jane,Rowlands Jane,Meadows Anne,O’Brien Criona,Rastall Rebecca,Crucusio Cherry,Hewitt Sarah,Price Jane,Calder Jo,Canna Laura,Bucke Ashlea,Tordesillas Hugo,Harris Julie,Ruffolo Valentina,Domingo Jason,Graves Barbara,Butcher Helen,Caputo Daniela,Le Gresley Emma,Dunmore Benjamin J.,Martin Jennifer,Legchenko Ekaterina,Treacy Carmen,Huang Christopher,Wood Jennifer,Sutcliffe Rachel,Hodgson Josh,Shih Joy,Graf Stefan,Tong Zhen,Mescia Federica,Tilly Tobias,O’Donnell Ciara,Hunter Kelvin,Pointon Linda,Pond Nicole,Wylot Marta,Jones Emma,Fawke Stuart,Bullman Ben,Turner Lori,Jarvis Isobel,Omarjee Ommar,De Sa Aloka,Marsden Joe,Betancourt Ariana,Perera Marianne,Epping Maddie,Richoz Nathan,Bower Georgie,Sharma Rahul,Nice Francesca,Huhn Oisin,Fawke Stuart,Savoinykh Yarkoni Natalia,Romashova Nika,Lewis Daniel,Hinch Andrew,Cossetti Chiara,Strezlecki Mateusz,Grenfell Richard,Stark Hannah,Walker Neil,Stirrups Kathy,Ovington Nigel,Dewhust Eleanor,Li Emily,Papadia Sofia,Kingston Nathalie,Lever Andrew,Torok Estee,Hamilton William,Hall Grant,Jahun Aminu,Chaudhry Yasmin,Pinckert Malte,Georgana Iliana,Yakovleva Anna,Caller Laura,Caddy Sarah,Feltwell Theresa,Khokhar Fahad,Meredith Luke,Holdcroft Charlotte,Curran Martin,Parmar Surendra,Kingston Nathalie,Lever Andrew,Torok Estee,Hamilton William,Hall Grant,Jahun Aminu,Chaudhry Yasmin,Pinckert Malte,Georgana Iliana,Yakovleva Anna,Caller Laura,Caddy Sarah,Feltwell Theresa,Khokhar Fahad,Meredith Luke,Holdcroft Charlotte,Curran Martin,Parmar Surendra

Funder

Wellcome Trust Senior Fellowship in Clinical Science

Wellcome Trust Clinical PhD Research Fellowship

National Institute for Health Research

Cambridge Biomedical Research Centre and the Cambridge Clinical Trials Unit

Medical Research Council

Wellcome Investigator Award

European Research Council

MRC

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference38 articles.

1. An interactive web-based dashboard to track COVID-19 in real time;Dong;Lancet Infect. Dis.,2020

2. Point of Care Nucleic Acid Testing for SARS-CoV-2 in Hospitalized Patients: A Clinical Validation Trial and Implementation Study;Collier;Cell Rep. Med.,2020

3. False-negative results of initial RT-PCR assays for COVID-19: a systematic review;Arevalo-Rodriguez;medRxiv,2020

4. Detection of SARS-CoV-2 in Different Types of Clinical Specimens;Wang;JAMA,2020

5. Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR;Fang;Radiology,2020

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