Phase 1a study of ESG401, a Trop2 antibody-drug conjugate, in patients with locally advanced/metastatic solid tumors

Author:

Wang Jiani,Tong Zhongsheng,Tan Yinuo,Shi Yehui,Wu Yun,Zhou Qing,Xing Xiaoyan,Chen Xiaomei,Qiu Fuming,Ma Fei

Funder

Chinese Academy of Medical Sciences & Peking Union Medical College

Science and Technology Commission of Shanghai Municipality

Publisher

Elsevier BV

Reference29 articles.

1. The emergence of trophoblast cell-surface antigen 2 (TROP-2) as a novel cancer target;Goldenberg;Oncotarget,2018

2. Prognostic role and clinical significance of trophoblast cell surface antigen 2 in various carcinomas;Xu;Cancer Manag. Res.,2017

3. Overexpression of TROP2 promotes proliferation and invasion of ovarian cancer cells;Wu;Exp. Ther. Med.,2017

4. The role of Trop2 in prostate cancer: an oncogene, biomarker, and therapeutic target;Shen;Am. J. Clin. Exp. Urol.,2021

5. Sacituzumab govitecan-hziy in refractory metastatic triple-negative breast cancer;Bardia;N. Engl. J. Med.,2019

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