Allosteric inhibition of SHP2 rescues functional T-cell abnormalities in SAP deficiency

Author:

Panchal NeelamORCID,Houghton Benjamin Christopher,Vassalou Elina,Thrasher Adrian J.,Booth Claire

Funder

Sanofi

NIHR Great Ormond Street Hospital Biomedical Research Centre

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference62 articles.

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2. Epstein-Barr virus--associated lymphoproliferative lesions;Harrington;Clin Lab Med,1988

3. Defective control of Epstein-Barr virus-infected B cell growth in patients with X-linked lymphoproliferative disease;Yasuda;Clin Exp Immunol,1991

4. Zhang K, Wakefield E, Marsh R. Lymphoproliferative disease, X-linked. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Mefford HC, et al., editors. GeneReviews. Seattle: University of Washington; 1993.

5. Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene;Coffey;Nat Genet,1998

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