Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels
Author:
Publisher
Elsevier BV
Subject
Immunology,Immunology and Allergy
Reference65 articles.
1. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma;Moffatt;Nature,2007
2. Interaction between genetic and epigenetic variation defines gene expression patterns at the asthma-associated locus 17q12-q21 in lymphoblastoid cell lines;Berlivet;Hum Genet,2012
3. Effect of 17q21 variants and smoking exposure in early-onset asthma;Bouzigon;N Engl J Med,2008
4. Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia;Ferreira;Eur J Hum Genet,2011
5. 17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry;Flory;J Allergy Clin Immunol,2009
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