Elevated hepatocyte growth factor levels in osteoarthritis osteoblasts contribute to their altered response to bone morphogenetic protein-2 and reduced mineralization capacity

Author:

Abed E.,Bouvard B.,Martineau X.,Jouzeau J.-Y.,Reboul P.,Lajeunesse D.

Funder

Canadian Institutes for Health Research

Osteoarthritis Chair of Excellence

Fondation Médicale pour la Recherche and la Région Lorraine

Publisher

Elsevier BV

Subject

Histology,Physiology,Endocrinology, Diabetes and Metabolism

Reference53 articles.

1. Biomechanical characteristics of iliac crest bone in elderly women, according to osteoarthritis grade at the hand joints;Gevers;J Rheumatol,1989

2. Physical and histomorphological characteristics of iliac crest bone differ according to the grade of osteoarthritis at the hand;Gevers;Bone,1989

3. Devos P, et al;Raymaekers;Alterations of the mineralization profile and osteocalcin concentrations in osteoarthritic cortical iliac crest bone, Calcif Tissue Int,1992

4. Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: Possible role in subchondral bone sclerosis;Hilal;Arthritis Rheum,1998

5. Endogenous prostaglandin E2 and insulin-like growth factor 1 can modulate the levels of parathyroid hormone receptor in human osteoarthritic osteoblasts;Hilal;J Bone Miner Res,2001

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