A novel semisynthesized small molecule icaritin reduces incidence of steroid-associated osteonecrosis with inhibition of both thrombosis and lipid-deposition in a dose-dependent manner

Author:

Zhang Ge,Qin Ling,Sheng Hui,Wang Xin-Luan,Wang Yi-Xiang,Yeung David Ka-Wai,Griffith James F.,Yao Xin-Sheng,Xie Xin-Hui,Li Zi-Rong,Lee Kwong-Man,Leung Kwok-Sui

Publisher

Elsevier BV

Subject

Histology,Physiology,Endocrinology, Diabetes and Metabolism

Reference45 articles.

1. Osteonecrosis: etiology, pathophysiology and diagnosis;Aaron,1998

2. Pathogenesis and natural history of osteonecrosis;Assouline-Dayan;Semin. Arthritis Rheum.,2002

3. Osteonecrosis of the hip: management in the 21st century;Lieberman;Instr. Course Lect.,2002

4. The pathogenesis and prevention of steroid-induced osteonecrosis;Wang;Clin. Orthop. Relat. Res.,2000

5. Hypofibrinolysis, thrombophilia, osteonecrosis;Glueck;Clin. Orthop. Relat. Res.,2001

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