Panobinostat clinical trial highlights the challenges towards an HIV cure
Author:
Publisher
Elsevier BV
Subject
Virology,Infectious Diseases,Immunology,Epidemiology
Reference5 articles.
1. Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial;Rasmussen;Lancet HIV,2014
2. The histone deacetylase inhibitor vorinostat (SAHA) increases the susceptibility of uninfected CD4+ T cells to HIV by increasing the kinetics and efficiency of postentry viral events;Lucera;J Virol,2014
3. The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function;Macintyre;Cell Metab,2014
4. Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection;Palmer;AIDS,2014
5. The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time;Josefsson;Proc Natl Acad Sci USA,2013
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Immunometabolism may provide new insights into novel mechanisms of HIV reservoir persistence;AIDS;2016-11-28
2. Glucose Metabolism in T Cells and Monocytes: New Perspectives in HIV Pathogenesis;EBioMedicine;2016-04
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