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cGAS activation causes lupus-like autoimmune disorders in a TREX1 mutant mouse model

  • Published:2019-06 Issue: Volume:100 Page:84-94
  • ISSN:0896-8411
  • Container-title:Journal of Autoimmunity
  • language:en
  • Short-container-title:Journal of Autoimmunity

Author:

Xiao Nanyang,Wei Jingjing,Xu Shan,Du Hekang,Huang Miaohui,Zhang Sitong,Ye Weiwei,Sun Lijun,Chen Qi

Funder

Fujian Key Laboratories Funds

Fujian Provincial Industrial Technology Development and Application Project

Fujian Bairen Program Funds

Fujian Normal University Key Laboratory Construction Funds

Fujian Normal University Start-up Funds

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference39 articles.

1. Nucleic acid driven sterile inflammation;Ablasser;Clin. Immunol.,2013

2. Microbial sensing by Toll-like receptors and intracellular nucleic acid sensors;Pandey;Cold Spring Harb. Perspect. Biol.,2014

3. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity;Kawai;Immunity,2011

4. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA;Wu;Science,2013

5. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway;Sun;Science,2013

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