Pharmacokinetics and metabolism in early drug discovery

Author:

Smith Dennis A,Waterbeemd Han van de

Publisher

Elsevier BV

Subject

Biochemistry,Analytical Chemistry

Reference52 articles.

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3. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings;Lipinski;Adv Drug Del Rev,1997

4. pH-metric solubility. 1. Solubility-pH profiles from Bjerrum plots. Gibbs buffer and pKa in the solid state;Avdeef;Pharm Pharmacol Commun,1998

5. Multiwavelength spectrophotometric determination of acid dissociation constants of ionizable drugs;Allen;J Pharm Biomed Anal,1998

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