Elevated Free Fatty Acid Concentrations in Lipemic Sera Reduce Protein Binding of Valproic Acid Significantly More Than Phenytoin-Reference-Cited by-同舟云学术

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Elevated Free Fatty Acid Concentrations in Lipemic Sera Reduce Protein Binding of Valproic Acid Significantly More Than Phenytoin

Published:1997-01 Issue:2 Volume:313 Page:75-79
ISSN:0002-9629
Container-title:The American Journal of the Medical Sciences
language:en
Short-container-title:The American Journal of the Medical Sciences

Author:

Dasgupta Amitava,Crossey Michael J.

Publisher

Elsevier BV

Subject

General Medicine

Reference17 articles.

1. Pharmacokinetics and bio-availability of sodium valproate;Klots;Clin Pharmacol Ther,1977

2. Valproic acid binding to human serum albumin and determination of free fraction in the presence of anti-epileptics and free fatty acids;Patel;Epilepsia,1979

3. Valproic acid: in vitro plasma protein binding and interaction with phenytoin.;Cramer;Ther Drug Monit.,1979

4. Absorption and distribution of anti-epileptic drugs;Meinardi;Epilepsia,1982

5. Clinical utility of unbound anti-epileptic drug blood levels in the management of epilepsy;Lenn;Neurology,1992

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