Localized delivery of Roxadustat via cubosomes-based thermosensitive in-situ hydrogel enhances diabetic wound healing by stabilizing HIF-1α in rats

Author:

Nasr MohamedORCID,Kira Ahmed Y.ORCID,Saber SamehORCID

Funder

STDF

Publisher

Elsevier BV

Reference47 articles.

1. Diabetic wound management;Rekha;Br. J. Community Nurs.,2018

2. Observed impact of skin substitutes in lower extremity diabetic ulcers: lessons from the Medicare Database (2015–2018);Armstrong;J. Wound Care,2021

3. Deferoxamine-loaded transfersomes accelerates healing of pressure ulcers in streptozotocin-induced diabetic rats;El-Gizawy;J. Drug Deliv. Sci. Technol.,2020

4. A small molecule HIF-1α stabilizer that accelerates diabetic wound healing;Li;Nat. Commun.,2021

5. Roxadustat promotes angiogenesis through HIF‐1α/VEGF/VEGFR2 signaling and accelerates cutaneous wound healing in diabetic rats;Zhu;Wound Repair Regen.,2019

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