Analysis of strand biased ’G’·C hypermutation in human immunoglobulin Vλ gene segments suggests that both DNA strands are targets for deamination by activation-induced cytidine deaminase
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Immunology
Reference28 articles.
1. Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion;Arakawa;Science,2002
2. Maturation of the immune response in germinal centers;Berek;Cell,1991
3. Sequence analysis of light chain genes from human plasma cells demonstrates that lambda genes are almost all in-frame and highly mutated and most kappa genes are highly mutated when in-frame and minimally mutated when out-of-frame;Boursier;Eur. J. Immunol.,2000
4. Imprint of somatic hypermutation differs in human immunoglobulin heavy and lambda chain variable gene segments;Boursier;Mol. Immunol.,2003
5. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase;Bransteitter;Proc. Natl. Acad. Sci. U.S.A.,2003
Cited by 14 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Activation‐induced cytidine deaminase can target multiple topologies of double‐stranded DNA in a transcription‐independent manner;The FASEB Journal;2020-05-21
2. The V H repertoire and clonal diversification of B cells in inflammatory myopathies;European Journal of Immunology;2014-01-16
3. Analysis of activation-induced cytidine deaminase mRNA levels in patients with chronic lymphocytic leukemia with different cytogenetic status;Leukemia & Lymphoma;2013-07-15
4. Somatic hypermutation and antigen-driven selection of B cells are altered in autoimmune diseases;Journal of Autoimmunity;2010-12
5. Mutagenesis dependent upon the combination of activation-induced deaminase expression and a double-strand break;Molecular Immunology;2010-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3