Characterization of a unique conformational epitope on free immunoglobulin kappa light chains that is recognized by an antibody with therapeutic potential-Reference-Cited by-同舟云学术

Characterization of a unique conformational epitope on free immunoglobulin kappa light chains that is recognized by an antibody with therapeutic potential

Published:2011-05 Issue:9-10 Volume:48 Page:1245-1252
ISSN:0161-5890
Container-title:Molecular Immunology
language:en
Short-container-title:Molecular Immunology

Author:

Hutchinson Andrew T.,Alexova Ralitza,Bockhorni Vanessa,Ramsland Paul A.,Jones Darren R.,Jennings Cameron V.,Broady Kevin,Edmundson Allen B.,Raison Robert L.

Funder

Immune System Therapeutics Ltd., Australia

National Health and Medical Research Council of Australia (NHMRC)

Publisher

Elsevier BV

Subject

Molecular Biology,Immunology

Reference28 articles.

1. Cellular and Molecular Immunology;Abbas,2007

2. Deficiency of kappa-or lambda-type immunoglobulins;Barandun;Blood,1976

3. Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties;Bourne;Acta Crystallogr. D: Biol. Crystallogr.,2002

4. A tumor-associated antigen specific for human kappa myeloma cells;Boux;J. Exp. Med.,1983

5. Serum Free Light Chain Analysis;Bradwell,2008

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