Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration-Reference-Cited by-同舟云学术

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Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration

Published:2024-01 Issue: Volume:165 Page:29-41
ISSN:0161-5890
Container-title:Molecular Immunology
language:en
Short-container-title:Molecular Immunology

Author:

Jindal Siddharth,Pedersen Dennis Vestergaard,Gera Nimish,Chandler Julian,Patel Rekha,Neill Alyssa,Cone Josh,Zhang Yuchun,Yuan Chao-Xing,Millman Ellen E.,Carlin Dan,Puffer Bridget,Sheridan Douglas,Andersen Gregers Rom,Tamburini Paul

Publisher

Elsevier BV

Subject

Molecular Biology,Immunology

Reference35 articles.

1. Towards automated crystallographic structure refinement with phenix.refine;Afonine;Acta Crystallogr. D. Biol. Crystallogr.,2012

2. Complement activation, regulation, and molecular basis for complement-related diseases;Bajic;EMBO J.,2015

3. Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria;Brodsky;Blood,2008

4. Current developments in coot for macromolecular model building of electron cryo-microscopy and crystallographic data;Casanal;Protein Sci.,2020

5. Characterization of multivalent complexes formed in the presence of more than one conventional antibody to terminal complement component C5;Cone;PLoS One,2023

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1. Phage display technology and its impact in the discovery of novel protein-based drugs;Expert Opinion on Drug Discovery;2024-06-18

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