Damnacanthal inhibits IgE receptor-mediated activation of mast cells

Author:

Garcia-Vilas Javier A.,Medina Miguel A.,Melo Fabio R.,Pejler Gunnar,Garcia-Faroldi Gianni

Funder

Swedish Cancer Foundation

Swedish Research Council

King Gustaf V's 80-year Anniversary Fund

Andalusian Government and FEDER

Publisher

Elsevier BV

Subject

Molecular Biology,Immunology

Reference28 articles.

1. Cytotoxic effect of damnacanthal, nordamnacanthal, zerumbone and betulinic acid isolated from Malaysian plant sources;Alitheen;Int. Food Res. J.,2010

2. Anticancer activity of Morinda citrifolia (Noni) fruit: a review;Brown;Phytother. Res.,2012

3. Protein kinase Cdelta functions downstream of Ca2+ mobilization in FcepsilonRI signaling to degranulation in mast cells;Cho;J. Allergy Clin. Immunol.,2004

4. Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity;Faltynek;Biochemistry,1995

5. Immunomodulatory mast cells: negative, as well as positive, regulators of immunity;Galli;Nat. Rev. Immunol.,2008

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