Are endosomal trafficking parameters better targets for improving mAb pharmacokinetics than FcRn binding affinity?

Author:

Gurbaxani Brian,Dostalek Miroslav,Gardner Iain

Publisher

Elsevier BV

Subject

Molecular Biology,Immunology

Reference116 articles.

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4. Biodistribution of monoclonal antibodies: scale-up from mouse to human using a physiologically based pharmacokinetic model;Baxter;Cancer Research,1995

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