The amino acid residue at position 95 and the third CDR region in the H chain determine the ceiling affinity and the maturation pathway of an anti-(4-hydroxy-3-nitrophenyl)acetyl antibody-Reference-Cited by-同舟云学术

The amino acid residue at position 95 and the third CDR region in the H chain determine the ceiling affinity and the maturation pathway of an anti-(4-hydroxy-3-nitrophenyl)acetyl antibody

Published:2010-11 Issue:1-3 Volume:48 Page:48-58
ISSN:0161-5890
Container-title:Molecular Immunology
language:en
Short-container-title:Molecular Immunology

Author:

Murakami Akikazu,Takahashi Yuka,Nishimura Miyuki,Shimizu Takeyuki,Azuma Takachika

Publisher

Elsevier BV

Subject

Molecular Biology,Immunology

Reference46 articles.

1. Antibody engineering for the analysis of affinity maturation of an anti-hapten response;Allen;EMBO J.,1988

2. Maturation of the immune response to (4-hydroxy-3-nitrophenyl)-acetyl (NP) haptens in C57BL/6 mice;Azuma;Mol. Immunol.,1987

3. Mutation of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer;Azuma;Int. Immunol.,1993

4. Molecular events during maturation of the immune response to oxazolone;Berek;Nature,1985

5. Elements regulating somatic hypermutation of an immunoglobulin κ gene: critical role for the intron enhancer/matrix attachment region;Betz;Cell,1994

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Influence of pre-B cell receptor deficiency on the immunoglobulin repertoires in peripheral blood B cells before and after immunization;Molecular Immunology;2024-02

2. Structural, functional, and physiological properties of anti-(4-hydroxy-3-nitrophenyl)acetyl antibodies during the course of affinity maturation;Biophysical Reviews;2022-10-20

3. A Trade-off Between Thermostability and Binding Affinity of Anti-(4-hydroxy-3-nitrophenyl)Acetyl Antibodies During the Course of Affinity Maturation;The Protein Journal;2022-04

4. Three-dimensional structure of a high affinity anti-(4-hydroxy-3-nitrophenyl)acetyl antibody possessing a glycine residue at position 95 of the heavy chain;Molecular Immunology;2019-10

5. Fine epitope mapping of a human disulphide-stabilized diabody against fibroblast growth factor-2;The Journal of Biochemistry;2018-12-31