A novel domain antibody rationally designed against TNF-α using variable region of human heavy chain antibody as scaffolds to display antagonistic peptides

Author:

Qin Weisong,Feng Jiannan,Li Yan,Lin Zhou,Shen Beifen

Publisher

Elsevier BV

Subject

Molecular Biology,Immunology

Reference35 articles.

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2. The biology of cachetin/TNF. A primary mediator of the host response;Beutler;Annu. Rev. Immunol.,1989

3. Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies;Brockhaus;Proc. Natl. Acad. Sci. U.S.A.,1990

4. A peptidomimetic antagonist of TNF-α mediated cytotoxicity identified from a phage-displayed random peptide library;Chirinos-Rojas;J. Immunol.,1998

5. Conformations of immunoglobulin hypervariable regions;Chothia;Nature,1989

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