A parenteral docetaxel-loaded lipid microsphere with decreased 7-epidocetaxel conversion in vitro and in vivo

Author:

Luo Lifeng,Wang Xiuzhi,Chen Qiuyue,Miao Linlin,Zhuo Xuezhi,Liu Lu,Xu Jiawen,Zhang Yu,He Haibing,Yin Tian,Tang Xing

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference40 articles.

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2. Docetaxel (Taxotere) is not metabolized by recombinant human CYP1B1 in vitro, but acts as an effector of this isozyme;Bournique;Drug Metab. Dispos.,2002

3. Formulation and preparation of a stable intravenous disulfiram-loaded lipid emulsion;Chen;Eur. J. Lipid Sci. Technol.,2015

4. Clinical pharmacokinetics of docetaxel;Clarke;Clin. Pharmacokinet.,1999

5. Evidence for the conversion of docetaxel into 7′-epidocetaxel in patients receiving Taxotere-based conventional chemotherapy;Czejka;Int. J. Clin. Pharmacol. Ther.,2010

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