First-in-human study on pharmacokinetics, safety, and tolerability of single and multiple escalating doses of PA9159 nasal spray, a highly potent glucocorticoid in healthy Chinese volunteers

Author:

Guo Shaojie,Hu Yingchun,Wang Chengshuo,Zhang Yuan,Wu Feng,Ni Siyang,Dai Yuyang,Han Ying,Hu Minwan,Lu Chunping,Xi Zhijian,Lu Laichun,Zhao XiuliORCID,Zhang Luo

Publisher

Elsevier BV

Reference21 articles.

1. Absolute bioavailability of intranasal fluticasone furoate in healthy subjects;Allen;Clin. Ther.,2007

2. Pharmacokinetics, safety, and tolerability of once-daily intranasal fluticasone furoate and levocabastine administered alone or simultaneously as fluticasone furoate/levocabastine fixed-dose combination;Allen;Clin. Pharmacol. Drug Dev.,2016

3. Once daily intranasal fluticasone propionate is effective for perennial allergic rhinitis;Banov;Ann. Allergy,1994

4. Intranasal steroids versus placebo or no intervention for chronic rhinosinusitis;Chong;Cochrane Database Syst. Rev.,2016

5. Systemic bioavailability of fluticasone propionate administered as nasal drops and aqueous nasal spray formulations;Daley-Yates;Br. J. Clin. Pharmacol.,2001

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