Top-down and bottom-up modeling in system pharmacology to understand clinical efficacy: An example with NRTIs of HIV-1
Author:
Funder
BMBF e:Bio junior research group ‘Systems Pharmacology & Disease Control’
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference68 articles.
1. Pharmacological considerations for tenofovir and emtricitabine to prevent HIV infection;Anderson;J. Antimicrob. Chemother.,2011
2. Phase I/II trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults;Barditch-Crovo;Antimicrob. Agents Chemother.,2001
3. Intracellular pharmacokinetics of antiretroviral drugs in HIV-Infected patients, and their correlation with drug action;Bazzoli;Clin. Pharmacokinet.,2010
4. Steady-state pharmacokinetics of emtricitabine and tenofovir disoproxil fumarate administered alone and in combination in healthy volunteers;Blum;J. Clin. Pharmacol.,2007
5. The stoichiometry of gag protein in HIV-1;Briggs;Nat. Struct. Mol. Biol.,2004
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