Inhibition of glycosylation on a camelid antibody uniquely affects its FcγRI binding activity

Author:

Krahn Natalie,Spearman Maureen,Meier Markus,Dorion-Thibaudeau July,McDougall Matthew,Patel Trushar R.,De Crescenzo Gregory,Durocher Yves,Stetefeld Jörg,Butler Michael

Funder

NSERC

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference71 articles.

1. Impact of glycosylation on effector functions of therapeutic IgG;Abès;Pharmaceuticals,2010

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3. Stable expression of chimeric heavy chain antibodies in CHO cells;Agrawal;Methods Mol. Biol.,2012

4. NMR analysis demonstrates immunoglobulin G N-glycans are accessible and dynamic;Barb;Nat. Chem. Biol.,2011

5. NMR characterization of immunoglobulin G Fc glycan motion on enzymatic sialylation;Barb;Biochemistry,2012

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