Excretion of the dipeptidyl peptidase-4 inhibitor linagliptin in rats is primarily by biliary excretion and P-gp-mediated efflux
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference16 articles.
1. The metabolism and disposition of the oral dipeptidyl peptidase-4 inhibitor, linagliptin, in humans;Blech;Drug Metab. Dispos.,2010
2. Overview of the gliptin class (dipeptidyl peptidase-4 inhibitors) in clinical practice;Bohannon;Postgrad. Med.,2009
3. Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes;Deacon;Expert Opin. Invest. Drugs,2010
4. Effect of linagliptin monotherapy on glycaemic control and markers of β-cell function in patients with inadequately controlled type 2 diabetes: a randomised controlled trial;Del Prato;Diab. Obes. Metab.,2011
5. Tissue distribution of the novel DPP-4 inhibitor BI 1356 is dominated by saturable binding to its target in rats;Fuchs;Biopharm. Drug Dispos.,2009
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