Assessing extent of brain penetration in vivo (Kp,uu,brain) in Göttingen minipig using a diverse set of reference drugs-Reference-Cited by-同舟云学术

Assessing extent of brain penetration in vivo (Kp,uu,brain) in Göttingen minipig using a diverse set of reference drugs

Published:2023-11 Issue: Volume:190 Page:106554
ISSN:0928-0987
Container-title:European Journal of Pharmaceutical Sciences
language:en
Short-container-title:European Journal of Pharmaceutical Sciences

Author:

Langthaler Kristine,Jones Christopher R.^ORCID,Brodin Birger,Bundgaard Christoffer

Funder

H Lundbeck A/S

Innovation Fund

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference69 articles.

1. FDA and industry collaboration: identifying opportunities to further reduce reliance on nonhuman primates for nonclinical safety evaluations;Ackley;Regul. Toxicol. Pharmacol.,2023

2. The influence of nonspecific microsomal binding on apparent intrinsic clearance, and its prediction from physicochemical properties;Austin;Drug Metab. Dispos.,2002

3. Diphenhydramine as a selective probe to study H(+)-antiporter function at the blood-brain barrier: application to [(11)C]diphenhydramine positron emission tomography imaging;Auvity;J. Cereb. Blood Flow Metab.,2017

4. Protein expression and functional relevance of efflux and uptake drug transporters at the blood-brain barrier of human brain and glioblastoma;Bao;Clin. Pharmacol. Ther.,2020

5. The utility of the minipig as an animal model in regulatory toxicology;Bode;J. Pharmacol. Toxicol. Methods,2010

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