Safety, pharmacokinetics and exploratory exposure-response analysis of CX3002, a novel inhibitor of Xa, in Chinese healthy subjects

Author:

Chen Wenjun,Ruan Zourong,Lou Honggang,Wang Lu,Shao Rong,Li Fenghua,Jiang Bo

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference27 articles.

1. Clinical laboratory measurement of direct factor Xa inhibitors: anti-Xa assay is preferable to prothrombin time assay;Barrett;Thromb. Haemost.,2010

2. Population pharmacokinetics, pharmacodynamics, and exploratory exposure-response analyses of apixaban in subjects treated for venous thromboembolism;Byon;CPT Pharmacomet. Syst. Pharmacol.,2017

3. Apixaban: a clinical pharmacokinetic and pharmacodynamic review;Byon;Clin. Pharmacokinet.,2019

4. Population pharmacokinetics of apixaban in subjects with nonvalvular atrial fibrillation;Cirincione;CPT Pharmacomet. Syst. Pharmacol.,2018

5. European Medicines Agency, 2022. Eliquis–Summary of Product Characteristics. Available online: https://www.ema.europa.eu/en/documents/product-information/eliquis-epar-product-information_en.pdf. Last accessed 2023 Mar 18.

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