Mitoxantrone, pixantrone and mitoxantrone (2-hydroxyethyl)piperazine are toll-like receptor 4 antagonists, inhibit NF-κB activation, and decrease TNF-alpha secretion in primary microglia
Author:
Funder
European Union Seventh Framework Programme
Business Finland
Academy of Finland
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference75 articles.
1. Pathogen Recognition and Innate Immunity;Akira;Cell,2006
2. Role of adapters in Toll-like receptor signalling;Akira;Biochem. Soc. Trans.,2003
3. Pivotal Advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis;Andersson;J. Leukoc. Biol.,2008
4. Seven Year Itch: pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations;Baell;ACS Chem. Biol.,2018
5. Function and Activation of NF-kappaB in the Immune System;Baeuerle;Annu. Rev. Immunol.,1994
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Insights into the computer-aided drug design and discovery based on anthraquinone scaffold for cancer treatment: A systematic review;PLOS ONE;2024-05-22
2. Development of Piperazine- and Oxazine-Linked Pyrimidines as p65 Subunit Binders of NF–κB in Human Breast Cancer Cells;Biomedicines;2023-10-06
3. Lotus Seedpod Oligomeric Procyanidin Nanoliposomes Targeting TLR4/NF-κB Reduce Inflammation and Oxidative Stress in Patients with Traumatic Brain Injury;Journal of Biomedical Nanotechnology;2023-10-01
4. Identification of PIMREG as a novel prognostic signature in breast cancer via integrated bioinformatics analysis and experimental validation;PeerJ;2023-07-17
5. Electroacupuncture at Fengchi(GB20) and Yanglingquan(GB34) Ameliorates Paralgesia through Microglia-Mediated Neuroinflammation in a Rat Model of Migraine;Brain Sciences;2023-03-24
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3