Pharmacokinetics of an anti-TFPI monoclonal antibody (concizumab) blocking the TFPI interaction with the active site of FXa in Cynomolgus monkeys after iv and sc administration

Author:

Agersø Henrik,Overgaard Rune Viig,Petersen Mads Bjelke,Hansen Lene,Hermit Mette Brunsgaard,Sørensen Mette Høgh,Petersen Lars Christian,Hilden Ida

Publisher

Elsevier BV

Subject

Pharmaceutical Science

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3. Blocking of tissue factor pathway inhibitor (TFPI) shortens the bleeding time in rabbits with antibody induced haemophilia A;Erhardtsen;Blood Coagul. Fibrinolysis,1995

4. Approximations of the target-mediated drug disposition model and identifiability of model parameters;Gibiansky;J. Pharmacokinet. Pharmacodyn.,2008

5. Tissue factor and factor VIIa as therapeutic targets in disorders of hemostasis;Hedner;Annu. Rev. Med.,2008

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