Pharmacokinetic interaction between oltipraz and omeprazole in rats: Competitive inhibition of metabolism of oltipraz by omeprazole via CYP1A1 and 3A2, and of omeprazole by oltipraz via CYP1A1/2, 2D1/2, and 3A1/2-Reference-Cited by-同舟云学术

Pharmacokinetic interaction between oltipraz and omeprazole in rats: Competitive inhibition of metabolism of oltipraz by omeprazole via CYP1A1 and 3A2, and of omeprazole by oltipraz via CYP1A1/2, 2D1/2, and 3A1/2

Published:2007-12 Issue:4-5 Volume:32 Page:328-339
ISSN:0928-0987
Container-title:European Journal of Pharmaceutical Sciences
language:en
Short-container-title:European Journal of Pharmaceutical Sciences

Author:

Lee Dae Y.,Kim Jin W.,Lee Myung G.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference47 articles.

1. Determination of a chemopreventive agent, oltipraz, in rat plasma and urine by high-performance liquid chromatography;Bae;Res. Commun. Mol. Pathol. Pharmacol.,2001

2. Pharmacokinetic interaction between oltipraz and dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethylene dioxybiphenyl-2,2′-dicarboxylate (DDB) after single intravenous and oral administration to rats;Bae;J. Pharm. Pharmacol.,2003

3. Pharmacokinetic changes of oltipraz after intravenous and oral administration to rats with liver cirrhosis induced by dimethylnitrosamine;Bae;Int. J. Pharm.,2004

4. Effects of enzyme inducers and inhibitors on the pharmacokinetics of oltipraz in rats;Bae;J. Pharm. Pharmacol.,2005

5. Hepatic and intestinal first-pass effects of oltipraz in rats;Bae;Biopharm. Drug Dispos.,2005

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