Efficient brain uptake and distribution of an expanded CAG RNA inhibitor DB213 via intranasal administration
Author:
Funder
Lui Che Woo Institute of Innovative Medicine BRAIN Initiative
Chinese University of Hong Kong
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference54 articles.
1. Universal biological scaling and mortality;Azbel Mya;Proc. Natl. Acad. Sci.,1994
2. A pathogenicmechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity;Bañez-Coronel;PLoS Genet.,2012
3. Small Molecule Inhibitors Targeting Cag-repeat RNA Toxicity in Polyglutamine Diseases;Chan,2017
4. Pharmacokinetic correlation between in vitro hepatic microsomal enzyme kinetics and in vivo metabolism of imipramine and desipramine in rats;Chiba;J. Pharm. Sci.,1990
5. Long-acting intranasal insulin detemir improves cognition for adults with mild cognitive impairment or early-stage Alzheimer's disease dementia;Claxton;J. Alzheimers Dis.,2015
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Stem cell-derived extracellular vesicles in the therapeutic intervention of Alzheimer's Disease, Parkinson's Disease, and stroke;Theranostics;2024
2. A Novel Huntington’s Disease Assessment Platform to Support Future Drug Discovery and Development;International Journal of Molecular Sciences;2022-11-25
3. New idea to promote the clinical applications of stem cells or their extracellular vesicles in central nervous system disorders: Combining with intranasal delivery;Acta Pharmaceutica Sinica B;2022-08
4. CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration;Proceedings of the National Academy of Sciences;2021-05-04
5. Direct transport theory: From the nose to the brain;Direct Nose-to-Brain Drug Delivery;2021
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3